Cellular and gene therapy

Cellular transplantation and gene therapy.

Concise review: Nanoparticles and cellular carriers-allies in cancer imaging and cellular gene therapy?

Ineffective treatment and poor patient management continue to plague the arena of clinical oncology. The crucial issues include inadequate treatment efficacy due to ineffective targeting of cancer deposits, systemic toxicities, suboptimal cancer detection and disease monitoring. This has led to the quest for clinically relevant, innovative multifaceted solutions such as development of targeted ...

ژن درمانی Gene Therapy

Combination of cellular imaging and molecular analysis for evaluation of cellular gene therapy of RA

115 Methotrexate (MTX) inhibition of cytokine production: relationship with clinical outcome and genetic polymorphisms D Pascual-Salcedo1, P Sabina1, A Balsa1, ME Miranda1, J Martin2, M Pascual2, E Martín Mola1 1Servicios de Inmunología y Reumatologia Hospital La Paz, Spain 2CSIC, Granada, Spain Arthritis Res Ther 2003, 5 (suppl 1):115 Introduction: Downregulation of TNF-α levels in synovial fl...

Stem cells as cellular vehicles for gene therapy against glioblastoma.

Glioblastoma (GBM) is the most common and deadliest primary tumor in adults, with current treatments having limited specific and efficient delivery of therapeutic drugs to tumor sites or cells. Therefore, the development of alternative treatment options is urgently needed. Stem cells are considered as ideal cellular vehicles for gene therapy against glioblastoma. In this paper, we reviewed the ...